DisGeNET - a database of gene-disease associations

PDPK1, 3-phosphoinositide dependent protein kinase 1, 5170

N. diseases: 77; N. variants: 0

Disease: Mammary Neoplasms ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C1458155
Disease:	Mammary Neoplasms

Mammary Neoplasms

0.310

Biomarker

group

CTD_human

Immunohistochemical analysis of PDK1 expression in breast cancer.

24739482

2014

CUI:	C1458155
Disease:	Mammary Neoplasms

Mammary Neoplasms

0.310

PosttranslationalModification

group

BEFREE

Particularly, moderate to high level of PDK-1 phosphorylation was found in 86% of high-grade metastasised breast tumours.

16288304

2005