Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
During the follow up, 16 (5.84%) participants developed non proliferative DR and 9 (3.64%) progressed to PDR while the mean corpuscular volume (MCV) and red cell distribution width (RDW) MCV rose.
|
30103306 |
2019 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
Eighty-six eyes from 57 patients with diabetes (19 with no DR, 19 with non-proliferative DR [NPDR], and 19 with proliferative DR [PDR] who had undergone photocoagulation) and 10 eyes from 10 patients without diabetes were recruited.
|
31001668 |
2019 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
This paper summarizes the recent studies about CTGF on DR fibrosis for a comprehensive understanding of the role and mechanism of CTGF in PDR.
|
30225233 |
2018 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
Incidence rate ratios (IRRs) were estimated for patients with DME, PDR, and vision-threatening DR, compared with persons without these conditions, by using individual participant data followed by a standard inverse-variance meta-analysis (2-step analysis).
|
28472362 |
2017 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
sCD40L plasma concentrations were measured in 205 type 2 diabetes (T2DM) patients without DR (DWR; n=50) and with DR (n=155), the latter subdivided into non-proliferative diabetic retinopathy [NPDR; n=98 (63.2%)], or proliferative retinopathy [PDR; n=57 (36.8%)] patients.
|
30149416 |
2018 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
IGF1 was found to increase the T2DM susceptibility as well as advanced DR, i.e., PDR, while VEGFA was found to be associated with early DR stage, i.e., NPDR.
|
31473834 |
2020 |
Diabetic Retinopathy
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The diabetic cohort included four subgroups (35 eyes without diabetic retinopathy, 30 eyes with mild to moderate nonproliferative diabetic retinopathy [NPDR], 27 eyes with severe NPDR, and 26 eyes with PDR).
|
29677360 |
2018 |
Diabetic Retinopathy
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Rs10061133 in MIR449b is significantly associated with a decreased risk of PDR and sight-threatening DR in Caucasian patients with type 1 diabetes.
|
31546259 |
2019 |
Diabetic Retinopathy
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Thr21Met (T21M) and Ser89Asn (S89N) polymorphisms of the UTS2 gene were associated with the risk of developing diabetes and DR. M21M genotype frequencies were high in PDR (8.9% in diabetic control vs. 54.6% in PDR, P = 0.0092) group.
|
22587369 |
2012 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
We first conducted a genome-wide association study of 1007 individuals, comparing 570 subjects with ≥8 years duration without DR (controls) with 437 PDR (cases) in the Chinese discovery cohort.
|
23562823 |
2013 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
Serum levels of MCP-1 protein in patients classified as diabetic without retinopathy (DWR) and DR, including NPDR and PDR, were assayed by enzyme-linked immunosorbent assay.
|
25981750 |
2016 |
Diabetic Retinopathy
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A total of 650 participants (495 [76.2%] nonproliferative DR [NPDR], 155 proliferative DR [PDR]) were analyzed; 302 (46.5%) were women and mean (SD) age was 61 (10) years; 425 (65.4%) were white.
|
28448655 |
2017 |
Diabetic Retinopathy
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Any DR, vision-threatening DR (VTDR), treatment coverage rates (proportion of participants with proliferative DR [PDR], clinically significant macular edema [CSME], or both who had evidence of retinal scatter and focal laser treatment).
|
28318640 |
2017 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this cross-sectional study, we examined 33 eyes from 33 patients with diabetes mellitus who underwent a vitrectomy (non-proliferative DR [NPDR, n = 8]; PDR with simple vitreous haemorrhage [VH, n = 17]; or PDR with a fibrovascular proliferative membrane [FVM, n = 8]).
|
28299499 |
2018 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
The prevalence of DR was 43.1% (95% confidence interval 39.6%-46.6%), with mild, moderate, and severe NPDR and PDR to be 9.41%, 7.46%, 11.1%, and 12.1%, respectively.
|
28669781 |
2017 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
For accuracy, the severe and PDR groups were merged, representing the high-risk DR group for receiver operator characteristic analysis.
|
30933259 |
2019 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
Panretinal leakage index [mild NPDR (mean = 0.51%), moderate NPDR mean = 1.20%, severe NPDR (mean = 2.75%), and PDR (mean = 5.84%); P<2×10<sup>-16</sup>], panretinal ischemic index [mild NPDR (mean = 0.95%, moderate NPDR (mean = 1.37%), severe NPDR (mean = 2.80%), and PDR (mean = 9.53%); P<2×10<sup>-16</sup>], and panretinal microaneurysm count [mild NPDR (mean = 36), moderate NPDR (mean = 129), severe NPDR (mean = 203), and PDR (mean = 254); P<5×10<sup>-7</sup>] were strongly associated with DR severity.
|
31383482 |
2019 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
Eight haplotype-tagging SNPs of SERPING1 and C5 were genotyped in 570 subjects with type 2 diabetes: 295 DR patients (138 nonproliferative DR [NPDR] and 157 proliferative DR [PDR]) and 275 diabetic controls.
|
26989329 |
2016 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
Conventional MRI was performed in 45 diabetic patients, 30 of whom had diabetic retinopathy (DR) involvement (half PDR, and half NPDR) and 15 of whom were diabetic patients without retinopathy and with normal ophthalmologic examination.
|
27846040 |
2017 |
Diabetic Retinopathy
|
0.100 |
Biomarker
|
disease |
BEFREE |
The study population included 292 adults with diabetes, with and without DR. DR (better eye) was categorised as presence and absence of any DR; severity of DR (no vision-threatening DR (VTDR); severe non-proliferative DR (NPDR); PDR and/or clinically significant macular oedema and VTDR).
|
30361276 |
2019 |
Malaria
|
0.100 |
Biomarker
|
disease |
BEFREE |
This basic data are useful for treatment and malaria control program in Lao PDR.
|
22177111 |
2011 |
Malaria
|
0.100 |
Biomarker
|
disease |
BEFREE |
A cross-sectional malaria field survey was conducted in 3 highly endemic malaria districts (Xaysetha, Sanamxay, Phouvong) in Attapeu province, Lao PDR in 2015, to investigate the precise malaria endemicity in the area; 719 volunteers from these villages participated in the survey.
|
29261647 |
2017 |
Malaria
|
0.100 |
Biomarker
|
disease |
BEFREE |
Elements of effective community engagement: lessons from a targeted malaria elimination study in Lao PDR (Laos).
|
28914184 |
2017 |
Malaria
|
0.100 |
Biomarker
|
disease |
BEFREE |
Targeted malaria elimination (TME) in Lao PDR (Laos) included three rounds of mass drug administrations (MDA) against malaria followed by quarterly blood surveys in two villages in Nong District at Savannakhet Province.
|
29061133 |
2017 |
Malaria
|
0.100 |
Biomarker
|
disease |
BEFREE |
There is an urgent need to consider alternative, accelerated strategies to eliminate malaria in countries like Lao PDR, where there are a few remaining endemic areas.
|
29183370 |
2017 |