PDYN, prodynorphin, 5173

N. diseases: 197; N. variants: 13
Disease: Marijuana Abuse ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse 		0.310 GeneticVariation disease BEFREE In this case-control study of adult African Americans (n=476; 206 females, 270 males), we examined the association of the functional prodynorphin 68 bp (<i>PDYN</i> 68 bp) promoter repeats with categorical diagnoses of cannabis dependence (<i>Diagnostic and Statistical Manual of Mental Disorders-IV</i> criteria), as well as with a rapid dimensional measure of maximum lifetime cannabis exposure (the Kreek-McHugh-Schluger-Kellogg cannabis scale). 29713172 2018
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse 		0.310 Biomarker disease PSYGENET Absence of delta -9-tetrahydrocannabinol dysphoric effects in dynorphin-deficient mice. 11717384 2001