PDYN, prodynorphin, 5173

N. diseases: 197; N. variants: 13
Disease: Bradycardia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0428977
Disease: Bradycardia
Bradycardia 		0.300 Biomarker phenotype CTD_human Effects of dynorphin A(1-13) and of fragments of beta-endorphin on blood pressure and heart rate of anesthetized rats. 1676337 1991
CUI: C0428977
Disease: Bradycardia
Bradycardia 		0.300 Biomarker phenotype CTD_human Both dynorphin (1-13) and Leu-enkephalin administered s.c. to normal and morphine-tolerant rats, 30 min before blood vessel cannulation and testing, lowered the morphine ED50 for bradycardia. 6716269 1984
CUI: C0428977
Disease: Bradycardia
Bradycardia 		0.300 Biomarker phenotype CTD_human Differential cardiovascular effects of mu, delta and kappa opiate agonists at discrete hypothalamic sites in the anesthetized rat. 6131355 1983