|
Recurrent seizure
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Low frequency DBS of the VHC significantly delayed the occurrence of the first spontaneous recurrent seizure in the PPS model by ∼300%, from 19 to 56 days.
|
31208877 |
2020 |
|
Alzheimer's Disease
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Since microtubule - Tau organization and dynamics is central in axonal microtubule cytoskeleton and transport, tightly related to aging processes and Alzheimer's disease, our current study provides a compelling molecular explanation to the <i>in vivo</i> activity of SKIP, placing SKIP motif as a central focus for MT-based neuroprotection in tauopathies with axonal transport implications.
|
31632241 |
2019 |
|
Arteriosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis.
|
30601470 |
2019 |
|
Atherosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis.
|
30601470 |
2019 |
|
Gaucher Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
The objective of this work is to analyze the in vitro effect of PPS on inflammatory cytokines in cellular models of Gaucher and Fabry diseases, and to study its effect in Gaucher disease associated in vitro bone alterations.
|
31150494 |
2019 |
|
Malignant neoplasm of stomach
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Bioinformatic data indicated that the mRNA expression of all MT family members was almost lowly expressed in GC compared with normal gastric tissue (P<0.05), and patients with reduced mRNA expression of each individual MT member had inconsistent prognostic value (OS, FP, PPS), which depended on the individual isoform of MT.
|
31380415 |
2019 |
|
Stomach Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Bioinformatic data indicated that the mRNA expression of all MT family members was almost lowly expressed in GC compared with normal gastric tissue (P<0.05), and patients with reduced mRNA expression of each individual MT member had inconsistent prognostic value (OS, FP, PPS), which depended on the individual isoform of MT.
|
31380415 |
2019 |
|
Acute Cerebrovascular Accidents
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The randomized study of endovascular therapy with versus without intravenous tissue plasminogen activator in acute stroke with ICA and M1 occlusion (SKIP study).
|
30924762 |
2019 |
|
Tauopathies
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Since microtubule - Tau organization and dynamics is central in axonal microtubule cytoskeleton and transport, tightly related to aging processes and Alzheimer's disease, our current study provides a compelling molecular explanation to the <i>in vivo</i> activity of SKIP, placing SKIP motif as a central focus for MT-based neuroprotection in tauopathies with axonal transport implications.
|
31632241 |
2019 |
|
Anxiety
|
0.010 |
Biomarker
|
disease |
BEFREE |
They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R).
|
29434563 |
2018 |
|
Anxiety Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R).
|
29434563 |
2018 |
|
Mental disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Taken together, the findings argue for a relationship between the malleability of PPS, interoceptive accuracy, and an inclination toward aberrant ideation often associated with mental illness.
|
29653377 |
2018 |
|
Congenital cataract
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
INPP5K variant causes autosomal recessive congenital cataract in a Pakistani family.
|
28940338 |
2018 |
|
Presenile dementia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Using the British Present Psychiatric State-learning Disabilities assessment (PPS-LD) questionnaire the dementia signs were screened in 62, 22 and 44 individuals (> 35 year of age) with Down (DS, OMIM number 190685), Williams (WS, OMIM number, 194050), and Fragile X syndrome (FXS, OMIM number 309550), respectively.
|
29971948 |
2018 |
|
Mental Depression
|
0.010 |
Biomarker
|
disease |
BEFREE |
They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R).
|
29434563 |
2018 |
|
Depressive disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R).
|
29434563 |
2018 |
|
Fragile X Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Using the British Present Psychiatric State-learning Disabilities assessment (PPS-LD) questionnaire the dementia signs were screened in 62, 22 and 44 individuals (> 35 year of age) with Down (DS, OMIM number 190685), Williams (WS, OMIM number, 194050), and Fragile X syndrome (FXS, OMIM number 309550), respectively.
|
29971948 |
2018 |
|
Postpericardiotomy Syndrome
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Background Postpericardiotomy syndrome ( PPS ) is a common complication after cardiac surgery.
|
30571490 |
2018 |
|
Stress, Psychological
|
0.010 |
Biomarker
|
disease |
BEFREE |
We investigated the impact of a novel repeated prenatal psychological stress (prenatal predator exposure - PPS) during the last week of gestation in rats on offspring behaviours related to social interaction (play behaviour), open field test (OFT), forced swim test (FST) and sucrose preference test (SP) during the juvenile period and in adulthood.
|
29183765 |
2018 |
|
Dermatitis, Phototoxic
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Such blocking allows utilization of the bactericidal properties of chitosan to a greater extent, since chitosan is known to depress the PPS photosensitizing activity in PPS-PVP-CT complexes when using those in photodynamic therapy (PDT).
|
29795266 |
2018 |
|
Depressed mood
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
They reported their age, gender, nationality, marital status, education and employment status, and completed two psychological questionnaires (PPS-4 and the anxiety and depression scales of the Symptom Checklist-90-Revised, SCL 90-R).
|
29434563 |
2018 |
|
Dementia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Using the British Present Psychiatric State-learning Disabilities assessment (PPS-LD) questionnaire the dementia signs were screened in 62, 22 and 44 individuals (> 35 year of age) with Down (DS, OMIM number 190685), Williams (WS, OMIM number, 194050), and Fragile X syndrome (FXS, OMIM number 309550), respectively.
|
29971948 |
2018 |
|
Cardiovascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Two cohorts initially recruited to study predictors of cardiovascular disease (the PPS cohort and the GOT-MONICA cohort) were followed from 1990 to 2011.
|
28600978 |
2017 |
|
Congenital muscular dystrophy (disorder)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Altogether these data demonstrate that mutations in INPP5K cause a congenital muscular dystrophy syndrome with short stature, cataracts, and intellectual disability.
|
28190459 |
2017 |
|
Coronary Artery Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
In regions, like Switzerland, where CAD is the leading cause of SCD associated with competitions, screening for cardiovascular risk factors in addition to the current PPS recommendations might be indicated to improve detection of silent CAD and further decrease the incidence of SCD.
|
28350812 |
2017 |