PGR, progesterone receptor, 5241

N. diseases: 392; N. variants: 33
Disease: HER2 gene amplification ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1512127
Disease: HER2 gene amplification
HER2 gene amplification 		0.100 Biomarker disease BEFREE Most salivary gland type tumours of the breast are negative for oestrogen and progesterone receptor and lack HER2 gene amplification, therefore they are classified as 'triple negative' tumours. 28043647 2017
CUI: C1512127
Disease: HER2 gene amplification
HER2 gene amplification 		0.100 AlteredExpression disease BEFREE Triple-negative breast cancer (TNBC) is characterized by a lack of estrogen and progesterone receptor expression (ESR and PGR, respectively) and an absence of human epithelial growth factor receptor (ERBB2) amplification. 29115931 2017