Malignant neoplasm of stomach
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of forkhead box M1 and urokinase-type plasminogen activator in gastric cancer is associated with cancer progression and poor prognosis.
|
29344165 |
2017 |
Malignant neoplasm of stomach
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
The expression of the uPA system positively correlates with peritoneal metastasis of gastric cancer.
|
23985164 |
2013 |
Malignant neoplasm of stomach
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Expression of MMP-2 mRNA, uPA, and uPA-R mRNA in tumor tissues and > or =5 cm adjacent normal tissues from 67 cases of gastric cancer was studied using RT-PCR and Northern blot respectively.
|
15929171 |
2005 |
Malignant neoplasm of stomach
|
0.380 |
Biomarker
|
disease |
CTD_human |
Methylation status of the 32 randomly selected and 16 potential tumor-related genes was analyzed in 10 primary gastric cancers, and 42 genes (ABHD9, ADFP, ALDH1A3, ANXA5, AREG, BDNF, BMP7, CAV1, CDH2, CLDN3, CTSL, EEF1A2, F2R, FADS1, FSD1, FST, FYN, GPR54, GREM1, IGFBP3, IGFBP7, IRS2, KISS1, MARK1, MLF1, MSX1, MTSS1, NT5E, PAX6, PLAGL1, PLAU, PPIC, RBP4, RORA, SCRN1, TBX3, TFAP2C, TNFSF9, ULBP2, WIF1, ZNF177 and ZNF559) were methylated in at least one primary gastric cancer.
|
16367923 |
2006 |
Malignant neoplasm of stomach
|
0.380 |
Biomarker
|
disease |
BEFREE |
By comparing the two groups, u-PA and VEGF were positively correlated in gastric cancer tissue (P < 0.05). u-PA and VEGF were highly expressed in gastric cancer tissue, which could be used as the molecular biological indicators to predict the invasion and metastasis potential of gastric cancer.
|
27352182 |
2015 |
Malignant neoplasm of stomach
|
0.380 |
Biomarker
|
disease |
BEFREE |
Prognostic relevance of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in gastric cancer.
|
8624578 |
1996 |
Malignant neoplasm of stomach
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, multivariate analysis demonstrated that depth of tumor invasion, lymph node involvement and uPA expression were independent prognostic factors. uPA is a key factor in the PA system, being associated with a poor outcome of gastric cancer, and contributing not only to invasive activity, but also to angiogenesis.
|
12708473 |
2003 |
Malignant neoplasm of stomach
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
These results indicate that immunohistochemical combination analysis of uPA and E-cadherin expression may be a powerful aid in evaluating metastatic potential or the prognosis of patients with gastric cancer.
|
8625219 |
1995 |
Malignant neoplasm of stomach
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
Expression of urokinase-type plasminogen activator receptor and plasminogen activator inhibitor-1 in gastric cancer.
|
9794194 |
1998 |