PLAU, plasminogen activator, urokinase, 5328

N. diseases: 439; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 GeneticVariation disease BEFREE Association of putative functional variants in the PLAU gene and the PLAUR gene with myocardial infarction. 20518747 2010
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic disease CTD_human Acute myocardial infarction complicating urokinase infusion for total saphenous vein graft occlusion. 8416330 1993
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker disease CTD_human Acute myocardial infarction complicating urokinase infusion for total saphenous vein graft occlusion. 8416330 1993
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker disease CTD_human Femoral nerve palsy secondary to anticoagulant induced iliacus hematoma. A case report. 2174952 1991
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic disease CTD_human [The kinetics of plasma coagulation fibrinolysis levels in acute myocardial infarction before and after treatment with intravenous urokinase]. 1908371 1991
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker disease CTD_human [The kinetics of plasma coagulation fibrinolysis levels in acute myocardial infarction before and after treatment with intravenous urokinase]. 1908371 1991
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic disease CTD_human Femoral nerve palsy secondary to anticoagulant induced iliacus hematoma. A case report. 2174952 1991
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic disease CTD_human Unstable angina or non-Q wave infarction despite long-term aspirin: response to thrombolytic therapy with implications on mechanisms. 2382605 1990
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker disease CTD_human Unstable angina or non-Q wave infarction despite long-term aspirin: response to thrombolytic therapy with implications on mechanisms. 2382605 1990
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic disease CTD_human [Use of urokinase in acute myocardial infarction]. 3068399 1988
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker disease CTD_human [Use of urokinase in acute myocardial infarction]. 3068399 1988
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker disease CTD_human Intravenous urokinase in acute myocardial infarction. 3984876 1985
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic disease CTD_human Intravenous urokinase in acute myocardial infarction. 3984876 1985
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 Biomarker disease CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136 2014
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 Therapeutic disease RGD Coexpression of Smad7 and UPA attenuates carbon tetrachloride-induced rat liver fibrosis. 23018346 2012
CUI: C0151699
Disease: Intracranial Hemorrhage
Intracranial Hemorrhage 		0.500 Biomarker group RGD Mutant prourokinase with adjunctive C1-inhibitor is an effective and safer alternative to tPA in rat stroke. 21779364 2011
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 Biomarker disease RGD Fraxinus rhynchophylla ethanol extract attenuates carbon tetrachloride-induced liver fibrosis in rats via down-regulating the expressions of uPA, MMP-2, MMP-9 and TIMP-1. 20035854 2010
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Biomarker phenotype RGD Thrombus versus wall biological activities in experimental aortic aneurysms. 20016209 2010
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.500 Biomarker disease RGD Transcriptional activation of endothelial cells by TGFβ coincides with acute microvascular plasticity following focal spinal cord ischaemia/reperfusion injury. 19663807 2009
CUI: C0403823
Disease: Asthenozoospermia
Asthenozoospermia 		0.500 Biomarker disease CTD_human [Correlation of the content and expression of urokinase plasminogen activator with asthenospermia in rat models]. 18998460 2008
CUI: C0403823
Disease: Asthenozoospermia
Asthenozoospermia 		0.500 Biomarker disease RGD [Correlation of the content and expression of urokinase plasminogen activator with asthenospermia in rat models]. 18998460 2008
CUI: C1527311
Disease: Brain Edema
Brain Edema 		0.500 Biomarker phenotype RGD Blood brain barrier (BBB) dysfunction associated with increased expression of tissue and urokinase plasminogen activators following peripheral thermal injury. 18718505 2008
CUI: C0151699
Disease: Intracranial Hemorrhage
Intracranial Hemorrhage 		0.500 Biomarker group CTD_human Symptomatic intracranial haemorrhage after intra-arterial thrombolysis in acute ischaemic stroke: assessment of 294 patients treated with urokinase. 17308290 2007
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.500 Therapeutic disease CTD_human [Effectiveness of urokinase used in combination with batroxobin (DF-521) in rat model of focal cerebral ischemia-reperfusion]. 15181847 2004
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Therapeutic phenotype CTD_human [Preparation of thrombus-targeted urokinase liposomes and its thrombolytic effect in model rats]. 12830724 2003