PLTP, phospholipid transfer protein, 5360

N. diseases: 62; N. variants: 9
Disease: Cardiovascular Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 Biomarker group BEFREE Delineating this mechanism would represent the first step towards understanding PLTP-mediated lipid transfers, which may be important for treating lipoprotein abnormalities and cardiovascular disease. 29883800 2018
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 GeneticVariation group BEFREE Of interest, common PLTP variations that predict cardiovascular disease have been identified recently. 21973210 2012
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 AlteredExpression group BEFREE A gene score based on 2 PLTP single nucleotide polymorphisms is associated with lower PLTP transcription and activity, an increased number of HDL particles, smaller HDL size, and decreased risk of cardiovascular disease. 20644014 2010