PLTP, phospholipid transfer protein, 5360

N. diseases: 62; N. variants: 9
Disease: Atherosclerotic lesion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4703473
Disease: Atherosclerotic lesion
Atherosclerotic lesion 		0.030 AlteredExpression disease BEFREE As the macrophage is a key component of the atherosclerotic lesion and an important site of PLTP expression, we investigated the role of systemic and peripheral PLTP in macrophage cholesterol efflux and reverse cholesterol transport (RCT) in vivo. 19100548 2009
CUI: C4703473
Disease: Atherosclerotic lesion
Atherosclerotic lesion 		0.030 Biomarker disease BEFREE In an LDLR-deficient background, the human PLTP-expressing mouse line showed a 2.2-fold increased atherosclerotic lesion area. 17761633 2007
CUI: C4703473
Disease: Atherosclerotic lesion
Atherosclerotic lesion 		0.030 Biomarker disease BEFREE However, whether PLTP might participate directly in human atherosclerotic lesion formation is unknown. 12835223 2003