S1PR5, sphingosine-1-phosphate receptor 5, 53637

N. diseases: 20; N. variants: 0
Disease: Lymphopenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024312
Disease: Lymphopenia
Lymphopenia 		0.010 Biomarker disease BEFREE There are promising data suggesting that it may also have a direct neuroprotective property independent of peripheral lymphocytopenia.<b>Areas covered</b>: We reviewed the pharmacology and the clinical and radiological effects of siponimod.<b>Expert opinion</b>: The selective effect of siponimod on the S1P1 and S1P5 receptors offers a favorable side-effect profile and transient bradycardia can be avoided by dose titration. 31603362 2019