Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936349
Disease: Plaque, Amyloid
Plaque, Amyloid
0.030 Biomarker disease BEFREE We have also addressed the impact of TREM2 on β-amyloid plaques and tau pathology in Alzheimer's disease. 31481003 2019
CUI: C2936349
Disease: Plaque, Amyloid
Plaque, Amyloid
0.030 AlteredExpression disease BEFREE Up-regulation of TREM2 accelerates the reduction of amyloid deposits and promotes neuronal regeneration in the hippocampus of amyloid beta1-42 injected mice. 30790627 2019
CUI: C2936349
Disease: Plaque, Amyloid
Plaque, Amyloid
0.030 Biomarker disease BEFREE While multiple studies support a role for TREM2 in microglial recruitment to amyloid plaques, the chemoattractant factor modulating TREM2-dependent microglial responses has not been defined. 29587871 2018