NLGN3, neuroligin 3, 54413

N. diseases: 63; N. variants: 7
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE Neuroblastoma is the most common extracranial solid tumor of childhood, previous studies show synaptic protein neuroligin-3 (NLGN3) promotes glioma proliferation and growth, However, no investigation about the role of NLGN3 in neuroblastoma was reported. 31150649 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE We also show the potential of NLGN3 and PTTG1 in EVs for detecting glioma. 31410219 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.050 Biomarker disease BEFREE Recent studies on glioma implicate the neuroligin-3 ectodomain as a mitogen. 30242227 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.050 AlteredExpression disease BEFREE NLGN3 expression in glioma tissue was semi-quantitatively assessed by immunohistochemistry. 30094719 2018
CUI: C0017638
Disease: Glioma
Glioma 		0.050 AlteredExpression disease BEFREE NLGN3 stimulates several oncogenic pathways, such as early focal adhesion kinase activation upstream of PI3K-mTOR, and induces transcriptional changes that include upregulation of several synapse-related genes in glioma cells. 28959975 2017