|
Pituitary-dependent Cushing's disease
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The purpose of this study was to determine the association of hypokalemia with cortisol and ACTH levels in patients with CD.
|
31456238 |
2020 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cushing's disease (CD) is a spectrum of clinical manifestations due to adrenocorticotropic hormone-secreting pituitary adenoma.
|
31491582 |
2020 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Adrenocorticotropic hormone (ACTH)-secreting adenomas account for Cushing's disease (CD) which is the most common form of ACTH-dependent Cushing's syndrome (CS).
|
30488233 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Pituitary magnetic resonance imaging (MRI) revealed a 3.5 mm microadenoma and inferior petrosal sinus sampling of adrenocorticotropic hormone (ACTH) after corticotropin releasing hormone (CRH) stimulation confirmed ACTH-dependent CD.
|
31251726 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Next to the traditional tests, a cutoff of preoperative ACTH/cortisol ratio, an ultrasensitive late night salivary cortisol assay and the desmopressin test have been suggested as valid tools for the diagnosis and differential diagnosis of CD.
|
30130808 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
In human patients, somatic mutations in USP8 were identified as the underlying cause of adrenocorticotropic hormone (ACTH) releasing pituitary adenomas causing Cushing's disease (CD).
|
31845722 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
The diagnosis of acromegaly and adrenocorticotropin hormone-dependent Cushing's disease was confirmed.
|
31505284 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cushing's disease (CD) is a rare endocrine condition caused by a corticotroph pituitary tumor that produces adrenocorticotropic hormone.
|
31701434 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Its diagnosis relies on both biochemical tests (high-dose dexamethasone suppression test, ACTH level, corticotropin-releasing hormone test) to confirm ACTH-dependent CD and image studies (CT or MRI of chest, abdomen, and/or pelvis) for source localization.
|
31019854 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Moreover, clinical manifestations of CD may vary depending on hormonal activity; however, factors involved in the hormonal aggressiveness of adrenocorticotropic hormone (ACTH)-secreting pituitary tumors have not been fully clarified.
|
30474823 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Pharmacological targeting of HSF1 may be a promising treatment option for the control of excess ACTH secretion in CD.
|
30995664 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Age of patients ranged from 52 to 72, five females and one male, four with Cushing's disease and two with ectopic ACTH production, one from a pancreatic neuroendocrine tumor and one from medullary carcinoma of the thyroid.
|
31001560 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cushing's disease (CD) is a rare condition caused by adrenocorticotropic hormone (ACTH)-producing adenomas of the pituitary, which lead to hypercortisolism that is associated with high morbidity and mortality.
|
31717455 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Patients with Cushing's disease and ectopic ACTH producing tumors showed elevated levels of androgens and their metabolites when compared with healthy controls.
|
31201926 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We present an unusual case of Turner syndrome (TS) and Cushing disease (CD) in a young woman, admitted to our department seven years after a successful surgical removal of ACTH-secreting pituitary tumor.
|
31242778 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Three months later, he presented to the endocrine clinic with symptoms of Cushing's disease and was diagnosed with an adrenocorticotropic hormone secreting pituitary microadenoma.
|
30635306 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Successful reduction of ACTH secretion in a case of intractable Cushing's disease with pituitary Crooke's cell adenoma by combined modality therapy including temozolomide.
|
31130573 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cushing's disease (CD) is caused by a pituitary tumour that secretes adrenocorticotropin (ACTH) autonomously, leading to excess cortisol secretion from the adrenal glands.
|
31512305 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Prognostic usefulness of ACTH in the postoperative period of Cushing's disease.
|
31394502 |
2019 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
ACTH-secreting pulmonary carcinoids, like the corticotroph adenomas causing Cushing's disease, are often small and difficult to detect, and patients present with a gradual onset of the classical signs and symptoms of Cushing's syndrome, indistinguishable from the presentation of Cushing's disease.
|
29754641 |
2018 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Knosp grade 4 adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma is a rare cause of Cushing disease.
|
30431585 |
2018 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
An early post-operative ACTH suppression test can safely predict short- and long-term remission after surgery of Cushing's disease.
|
30039432 |
2018 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Long-term outcomes of tissue-based ACTH-antibody assay-guided transsphenoidal resection of pituitary adenomas in Cushing disease.
|
29027854 |
2018 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cushing's disease (CD) is a condition characterized by excess glucocorticoid from an ACTH pituitary adenoma.
|
29716804 |
2018 |
|
Pituitary-dependent Cushing's disease
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Cushing disease (CD) is a rare entity caused by ACTH-secreting pituitary tumours, leading to prolonged hypercortisolism.
|
29927501 |
2018 |