POMC, proopiomelanocortin, 5443

N. diseases: 873; N. variants: 39
Disease: Renal Cell Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.330 AlteredExpression disease BEFREE A 62-year-old man was referred to our department for elevation of plasma ACTH and cortisol levels during nivolumab administration for renal cell carcinoma. 31217401 2019
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.330 Biomarker disease BEFREE This also appears to be the first ACTH-staining adenoma concomitant with RCC reported in the literature, regardless of location, not presenting with Cushing disease. 28532906 2017
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.330 AlteredExpression disease BEFREE We confirmed that Nur77 and POMC are up-regulated in VHL-mutated renal cell carcinoma. 14729605 2004
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.330 Biomarker disease CTD_human We authors believe that this is the first documented case of ACTH-producing Grawitz tumor in the literature. 2844640 1988