|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Retrospective chart review of 75 hypertensive adults cured of CS (72 with ACTH-dependent CS; 3 with adrenal adenoma).
|
31721265 |
2020 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cushing's disease (CD) is a rare condition caused by adrenocorticotropic hormone (ACTH)-producing adenomas of the pituitary, which lead to hypercortisolism that is associated with high morbidity and mortality.
|
31717455 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
According to the role of adrenocorticotropic hormone (ACTH) in adrenal androgen secretion, it is not surprising that the levels of dehydroepiandrosterone, dehydroepiandrosterone-sulfate, and androstenedione (A4) are generally elevated or in the upper normal range in patients with ACTH-dependent CS.
|
31499501 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
We describe a patient with florid Cushing syndrome due to ectopic adrenocorticotropic hormone (ACTH) from a NET of colonic origin.
|
30314823 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Adrenal functional autonomy has been described in a subset of patients with CD, leading to the hypothesis of transition from ACTH-dependent to ACTH-independent hypercortisolism.
|
31276155 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
A diagnosis of ectopic ACTH-dependent CS was made.
|
28862247 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Bilateral adrenocortical adenomas causing adrenocorticotropic hormone-independent Cushing's syndrome: A case report and review of the literature.
|
31119141 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
All patients had suppressed 8 am adrenocorticotropic hormone (ACTH) (<10 pg/mL) despite evidence of hypercortisolism.
|
30875328 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
A bilateral inferior petrosal sinus sampling (BIPSS) performed during a trough phase was false positive for pituitary ACTH overproduction resulting in unnecessary transsphenoidal surgery while a second BIPSS performed during an active phase was indicative for ectopic CS.
|
31640675 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
SCLC-associated diabetes was related to EAS, which was an endogenous ACTH-dependent form of Cushing's syndrome with elevated ACTH and cortisol levels.
|
31183355 |
2019 |
|
Cushing Syndrome
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
It is uncertain whether thymic neuroendocrine tumors (NET) associated with Cushing's syndrome (CS) produce corticotropin-releasing hormone (CRH) and adrenocorticotropin hormone (ACTH) and whether the thymus contains ACTH and/or CRH cells that could originate NET.
|
30502716 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Surgical intervention, aimed at removing the source of cortisol or adrenocorticotropic hormone (ACTH), is the optimal treatment in most cases of Cushing's syndrome.
|
30800267 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
All patients with CS had hormone test including morning plasma-free cortisol, 24-hour urine-free cortisol (24UFC), and plasma adrenocorticotropic hormone.
|
29266048 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Additional biochemistry confirmed adrenocorticotropic hormone-independent hypercortisolism.
|
31492730 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
ACTH = adrenocorticotropic hormone; CS = Cushing syndrome; CT = computed tomography; DHEAS = dehydroepiandrosterone sulfate; HU = Hounsfield units; MRI = magnetic resonance imaging; UFC = urinary free cortisol.
|
30817193 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
We observed a case of ACTH-dependent cyclic Cushing syndrome that was developed by exogenous glucocorticoids, possibly through a glucocorticoid positive-feedback loop.
|
30561712 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
The management of patients with adrenocorticotropic hormone-independent Cushing's syndrome and bilateral adrenal masses is challenging.
|
31467526 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
The neurosurgical resection of her 2 mm adrenocorticotropic hormone (ACTH) secreting pituitary microadenoma resulted in a successful resolution of the patient's hypercortisolism and a significant recovery of her neurocognitive function.
|
31253144 |
2019 |
|
Cushing Syndrome
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Sixty-three (24.8%) tumors produced ACTH and 11 of them (17.4%), representing 4.3% of the whole series, were associated with Cushing syndrome.
|
31264037 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Investigations demonstrated adrenocorticotropic hormone-independent Cushing's syndrome with bilateral adrenal gland enlargement.
|
31362300 |
2019 |
|
Cushing Syndrome
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Preoperatively, incidentalomas + SH patients had larger tumors, higher ACTH, and DHEA-S but lower dexamethasone-suppressed serum cortisol levels than those with CS.
|
30259310 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
During investigation, an adrenocorticotropic hormone (ACTH) independent CS was identified and the possibility of an adrenocortical tumor was suggested.
|
30699069 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
Localization of ectopic ACTH-secreting tumours causing Cushing syndrome (ECS) is essential for clinical management, yet often difficult.
|
31066920 |
2019 |
|
Cushing Syndrome
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In this regard, impaired adrenocortical function is likely induced by atrophy of the residual adrenal tissue as a result of chronic suppression by the low ACTH levels of the hypercortisolism state.
|
30915117 |
2019 |
|
Cushing Syndrome
|
0.400 |
Biomarker
|
disease |
BEFREE |
A mono-centric and longitudinal study was conducted on 19 consecutive patients who underwent SBA for ACTH-dependent hypercortisolism between December 2003 and December 2017.
|
31583577 |
2019 |