PON1, paraoxonase 1, 5444

N. diseases: 496; N. variants: 29
Disease: Acute Coronary Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 GeneticVariation disease BEFREE Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome. 31772608 2019
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 Biomarker disease BEFREE Effects of Cardiac Rehabilitation on High-Density Lipoprotein-mediated Cholesterol Efflux Capacity and Paraoxonase-1 Activity in Patients with Acute Coronary Syndrome. 28855433 2018
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 Biomarker disease CTD_human Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population. 26241956 2015
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 GeneticVariation disease BEFREE Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population. 26241956 2015
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 Biomarker disease BEFREE Alteration of HDL functionality and PON1 activities in acute coronary syndrome patients. 25218815 2014
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 GeneticVariation disease BEFREE In conclusion, our study shows that PON1 Q192R genotype does not modify the efficacy and safety of clopidogrel in patients with acute coronary syndromes. 22368149 2012
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 GeneticVariation disease BEFREE We evaluated the possible relationships of HDL levels as well as PON-1 activities and the Q192R genotype with clopidogrel's antiplatelet efficacy in acute coronary syndrome (ACS) patients. 22008470 2011
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.370 GeneticVariation disease BEFREE Association of homocysteine thiolactonase activity and PON1 polymorphisms with the severity of acute coronary syndrome. 19269283 2009