Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia
0.010 Biomarker disease BEFREE RIF and ATO showed similar effects on the recovery of coagulopathy in APL patients. 29232592 2018
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.010 Biomarker group BEFREE RIF and ATO showed similar effects on the recovery of coagulopathy in APL patients. 29232592 2018
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement
0.100 GeneticVariation phenotype GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
CUI: C0238104
Disease: Chronic endometritis
Chronic endometritis
0.010 Biomarker disease BEFREE Recent evidences suggest that in apparently normal endometria, RIF may associate with molecular and functional changes in the uterus such as abnormal endometrial microbiota, including the presence of chronic endometritis, poor synchronization between the blastocyst and endometrium, and/or excessive uterine peristalsis. 29889670 2018
CUI: C0275524
Disease: Coinfection
Coinfection
0.010 Biomarker phenotype BEFREE The Xpert® MTB/RIF assay is being implemented as a substitute for sputum smear microscopy (SSM) in many low and high tuberculosis (TB) burden countries, including Brazil, a country with low multidrug resistance and moderate human immunodeficiency virus co-infection rates. 27084814 2016
CUI: C2747816
Disease: Complicated malaria
Complicated malaria
0.010 Biomarker disease BEFREE Here, antibody subclass responses to a recombinant RIFIN protein (RIF-29) in 116 Ghanaian children were determined by ELISA to investigate the relationship between severe malaria and anti-RIF-29 antibodies. 16679041 2006
Disseminated Intravascular Coagulation
0.010 Biomarker disease BEFREE RIF had a potential beneficial effect in accelerating the recovery of thrombocytopenia and hypofibrinogenemia for subclinical DIC patients. 29232592 2018
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.010 Biomarker disease BEFREE Abbreviations: AMs: adenomyosis; EMs: endometriosis; RIF: recurrent implantation failure; miRNAs: microRNAs; lncRNAs: Long non-coding RNAs; RT-qPCR: real-time quantitative PCR; ESCs: endometrial stromal cells; EECs: endometrial epithelial cells; BFE: free binding energy; PCDHB9: protocadherin beta 9; PARVG: parvin gamma; MAPK6: mitogen-activated protein kinase 6; LAF1: lymphocyte function-associated antigen 1. 30649983 2019
CUI: C0200638
Disease: Eosinophil count procedure
Eosinophil count procedure
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0341106
Disease: Eosinophilic esophagitis
Eosinophilic esophagitis
0.010 AlteredExpression disease BEFREE Finally, we find that RHOF is upregulated in eosinophilic esophagitis, an important esophageal inflammatory disease in humans. 30998758 2019
Extensively Drug-Resistant Tuberculosis
0.010 GeneticVariation phenotype BEFREE We conclude that the remnants of samples processed for the Xpert assay can be used in PCRs to find mutations associated with the resistance to the additional drugs that defines MDR and XDR-TB and to study molecular epidemiology without the need for culturing or a biosafe infrastructure. 28446574 2017
CUI: C4316812
Disease: Fibrinogen Deficiency
Fibrinogen Deficiency
0.010 Biomarker disease BEFREE RIF had a potential beneficial effect in accelerating the recovery of thrombocytopenia and hypofibrinogenemia for subclinical DIC patients. 29232592 2018
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
0.010 Biomarker group BEFREE Real-time PCR investigation for deletion of genes BCL7A, SMAC/DIABLO, and RHOF-three tumor suppressor genes with a putative role in hematological malignancies-demonstrated that they were deleted in 9, 10, and 13 cases, respectively. 18663754 2008
CUI: C0019158
Disease: Hepatitis
Hepatitis
0.010 Biomarker group BEFREE Sputum samples tested on Xpert for MTB/RIF assay and blood specimens collected for HIV and hepatitis serology. 31801496 2019
CUI: C0019159
Disease: Hepatitis A
Hepatitis A
0.010 Biomarker disease BEFREE Sputum samples tested on Xpert for MTB/RIF assay and blood specimens collected for HIV and hepatitis serology. 31801496 2019
CUI: C0497169
Disease: hiv-infection/aids
hiv-infection/aids
0.010 Biomarker disease BEFREE Cost Analysis of Tuberculosis Diagnosis in Cambodia with and without Xpert<sup>®</sup> MTB/RIF for People Living with HIV/AIDS and People with Presumptive Multidrug-resistant Tuberculosis. 29862440 2018
Human immunodeficiency virus (HIV) II infection category B1
0.050 Biomarker disease BEFREE The introduction of Xpert MTB/RIF assay (Xpert) has significantly improved diagnosis of Tuberculosis (TB) in resource limited human immunodeficiency virus (HIV) endemic settings. 29284421 2017
Human immunodeficiency virus (HIV) II infection category B1
0.050 Biomarker disease BEFREE Sputum samples tested on Xpert for MTB/RIF assay and blood specimens collected for HIV and hepatitis serology. 31801496 2019
Human immunodeficiency virus (HIV) II infection category B1
0.050 Biomarker disease BEFREE We assessed the performance of alternative specimen collection methods for tuberculosis diagnosis in HIV-infected children using Xpert MTB/RIF (Xpert). 26908804 2016
Human immunodeficiency virus (HIV) II infection category B1
0.050 Biomarker disease BEFREE The GX results of Primestore-stored samples were similar to those found in the fresh sputum of non-HIV infected patients, but GX-positivity was lower in HIV-infected patients. 31817201 2019
Human immunodeficiency virus (HIV) II infection category B1
0.050 GeneticVariation disease BEFREE Our results show high rates of DR-TB in Nigerian HIV-infected individuals (7.0% for rifampin [RIF] and 9.3% for RIF or isoniazid [INH]). 22740709 2012
CUI: C0020255
Disease: Hydrocephalus
Hydrocephalus
0.010 Biomarker disease BEFREE There was a significant association between CSF GeneXpert and Mantoux test (P = 0.002), CSF cell type >50% lymphocytes (P = 0.005) and CSF protein >100 mg/dl (P = 0.025) along with CT hydrocephalus (P = 0.021), granuloma (P = 0.009) and basal exudates (P = 0.025). 31359250 2019
CUI: C0553681
Disease: Hypofibrinogenemia
Hypofibrinogenemia
0.010 Biomarker disease BEFREE RIF had a potential beneficial effect in accelerating the recovery of thrombocytopenia and hypofibrinogenemia for subclinical DIC patients. 29232592 2018
Immune Reconstitution Inflammatory Syndrome
0.010 Biomarker disease BEFREE Five cases were false-positive by Xpert MTB/RIF in patients with nontuberculous mycobacteria, old PTB scar, and immune reconstitution syndrome. 28475796 2017
CUI: C1096197
Disease: Immune reconstitution syndrome
Immune reconstitution syndrome
0.010 Biomarker disease BEFREE Five cases were false-positive by Xpert MTB/RIF in patients with nontuberculous mycobacteria, old PTB scar, and immune reconstitution syndrome. 28475796 2017