POU4F1, POU class 4 homeobox 1, 5457

N. diseases: 54; N. variants: 0
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 AlteredExpression disease BEFREE SLNCR1, AR, and Brn3a are specifically required for transcriptional activation of matrix metalloproteinase 9 (MMP9) and increased melanoma invasion. 27210747 2016
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE Together, these results identify Brn3a as a new factor in melanoma that is essential for melanoma cell survival and that promotes melanocytic transformation and tumourigenesis. 23666755 2013