POU4F3, POU class 4 homeobox 3, 5459

N. diseases: 23; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007129
Disease: Merkel cell carcinoma
Merkel cell carcinoma
0.010 AlteredExpression disease LHGDN We propose that HATH1 and Brn-3c may form a transcriptional hierarchy responsible for determining neuroendocrine phenotype in Merkel cells and that lack of Brn-3c and/or HATH1 in MCC may indicate a more aggressive disease requiring closer patient follow-up. 12209986 2002
CUI: C0007129
Disease: Merkel cell carcinoma
Merkel cell carcinoma
0.010 Biomarker disease BEFREE We propose that HATH1 and Brn-3c may form a transcriptional hierarchy responsible for determining neuroendocrine phenotype in Merkel cells and that lack of Brn-3c and/or HATH1 in MCC may indicate a more aggressive disease requiring closer patient follow-up. 12209986 2002