TMEM106B, transmembrane protein 106B, 54664

N. diseases: 126; N. variants: 13
Disease: Dementia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0497327
Disease: Dementia
Dementia 		0.130 GeneticVariation disease BEFREE Among CTE cases, TMEM106B minor allele was also associated with reduced ante-mortem dementia (OR = 0.40, 95% CI 0.16-0.99, p = 0.048), but was not associated with TDP-43 pathology. 30390709 2018
CUI: C0497327
Disease: Dementia
Dementia 		0.130 GeneticVariation disease BEFREE A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression. 29056226 2017
CUI: C0497327
Disease: Dementia
Dementia 		0.130 GeneticVariation disease BEFREE Transmembrane protein 106B (TMEM106B) has been identified as a risk factor for frontotemporal lobar degeneration, which is the second most common form of progressive dementia in people under 65 years of age. 26651479 2015
CUI: C0497327
Disease: Dementia
Dementia 		0.130 Biomarker disease HPO