TMEM106B, transmembrane protein 106B, 54664

N. diseases: 126; N. variants: 13
Disease: Cerebral atrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235946
Disease: Cerebral atrophy
Cerebral atrophy 		0.120 GeneticVariation disease BEFREE Together, these results indicate that brain atrophy in presymptomatic carriers of common frontotemporal dementia mutations is affected by both genetic and environmental factors such that TMEM106B enhances the benefit of cognitive reserve on brain structure. 28460069 2017
CUI: C0235946
Disease: Cerebral atrophy
Cerebral atrophy 		0.120 GeneticVariation disease BEFREE Neither TMEM106B (rs1990622_T), KCNMB2 (rs9637454_A), nor any of the non-risk alleles were associated with brain atrophy. 27003218 2016
CUI: C0235946
Disease: Cerebral atrophy
Cerebral atrophy 		0.120 Biomarker disease HPO