Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE ARD1 contributes to IKKβ-mediated breast cancer tumorigenesis. 30154412 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 PosttranslationalModification phenotype BEFREE ARD1-dependent PGK1 acetylation and PGK1-mediated Beclin1 S30 phosphorylation are required for glutamine deprivation- and hypoxia-induced autophagy and brain tumorigenesis. 28238651 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 GeneticVariation phenotype BEFREE In the present study, we demonstrated that mARD1(225), mARD1(235), and hARD1(235) have conserved autoacetylation activities, and that they selectively regulate distinct roles of ARD1 variants in tumorigenesis. 25338643 2015
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Because AR-ARD1 interaction facilitated the AR binding to its targeted promoters for gene transcription, we propose that ARD1 functions as a unique AR regulator and forms a positive feedback loop for AR-dependent prostate tumorigenesis. 22315407 2012
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE To explore the clinical and pathological significance of ARD1 in breast tumorigenesis, we analyzed ARD1 status in multiple types of breast disease. 22292636 2011
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. 20145209 2010