SOX6, SRY-box transcription factor 6, 55553

N. diseases: 105; N. variants: 46
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.130 Biomarker disease BEFREE We demonstrate for the first time that SOX6 influence FFM and QUS trait in a population of young adults, suggesting the implication of this gene in obesity and osteoporosis-related phenotypes during early adulthood. 30062780 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.130 AlteredExpression disease BEFREE The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. 26893351 2016
CUI: C0028754
Disease: Obesity
Obesity 		0.130 GeneticVariation disease GWASCAT Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. 19714249 2009
CUI: C0028754
Disease: Obesity
Obesity 		0.130 Biomarker disease BEFREE Our findings, together with the prior biological evidence, suggest the SOX6 gene's importance in co-regulation of obesity and osteoporosis. 19714249 2009