Feeding behaviors
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A genome-wide investigation of food addiction.
|
27106561 |
2016 |
Leukemia, Myelocytic, Acute
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The protein encoded by FLJ10849 belongs to the septin family, sharing highest homology with human SEPT6, which is one of the fusion partners of MLL in t(X;11)(q13;q23) AML.
|
14999297 |
2004 |
Neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
In humans, 14 septin genes have been identified, of which five (SEPT2, SEPT5, SEPT6, SEPT9, and SEPT11) are known to participate in reciprocal translocations with the MLL gene in myeloid neoplasias.
|
19748670 |
2010 |
AMYOTROPHY, HEREDITARY NEURALGIC
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling.
|
17546647 |
2007 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A translocation in acute lymphoblastic leukemia that cytogenetically mimics the recurrent MLL-AFF1 translocation and fuses SEPT11 to MLL.
|
20633769 |
2010 |
Bipolar Disorder
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Common proteomic changes in the hippocampus in schizophrenia and bipolar disorder and particular evidence for involvement of cornu ammonis regions 2 and 3.
|
21536977 |
2011 |
Schizophrenia
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Common proteomic changes in the hippocampus in schizophrenia and bipolar disorder and particular evidence for involvement of cornu ammonis regions 2 and 3.
|
21536977 |
2011 |
Methylmalonic acidemia
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Quantitative analysis of mitochondrial protein expression in methylmalonic acidemia by two-dimensional difference gel electrophoresis.
|
16823967 |
2006 |
Methylmalonic aciduria
|
0.300 |
Biomarker
|
disease |
CTD_human |
Quantitative analysis of mitochondrial protein expression in methylmalonic acidemia by two-dimensional difference gel electrophoresis.
|
16823967 |
2006 |
Down Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Quantitative analysis of hypothetical protein FLJ10849, hypothetical protein FLJ20113, and activator of hsp90 ATPase homologue 1 (AHA1) revealed levels comparable between DS and controls.
|
15176487 |
2004 |
leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results suggest that FLJ10849 might define a new septin family particularly involved in the pathogenesis of 11q23-associated leukemia.
|
14999297 |
2004 |
Obesity
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our findings support a role for SEPT11 in lipid traffic and metabolism in adipocytes and open new avenues for research on the control of lipid storage in obesity and insulin resistance.
|
27866222 |
2017 |
Frontotemporal Lobar Degeneration
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here, we describe the identification of septin 11 (SEPT11), an enriched component of detergent-resistant fractions in frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions (FTLD-U), using large-scale unbiased proteomics approaches.
|
22126117 |
2011 |
Childhood Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results suggest that FLJ10849 might define a new septin family particularly involved in the pathogenesis of 11q23-associated leukemia.
|
14999297 |
2004 |
Differentiated Thyroid Gland Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In addition, we confirmed three previously reported loci (FOXE1, NKX2-1 and DIRC3) and identified seven novel susceptibility loci (VAV3, PCNXL2, INSR, MRSB3, FHIT, SEPT11 and SLC24A6) associated with DTC.
|
28703219 |
2017 |
Liver carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
LOH in ARD1B and SEPT11 could serve as novel prognostic predictors in HCC patients.
|
20419844 |
2010 |
GRN-related frontotemporal dementia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here, we describe the identification of septin 11 (SEPT11), an enriched component of detergent-resistant fractions in frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions (FTLD-U), using large-scale unbiased proteomics approaches.
|
22126117 |
2011 |
MIXED LINEAGE LEUKEMIA
|
0.010 |
Biomarker
|
disease |
BEFREE |
Five different septin genes (SEPT2, SEPT5, SEPT6, SEPT9, and SEPT11) have been identified as MLL fusion partners, giving rise to chimeric fusion proteins in which the N terminus of MLL is fused, in frame, to almost the entire open reading frame of the septin partner gene.
|
21714766 |
2011 |
Complete Trisomy 21 Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Quantitative analysis of hypothetical protein FLJ10849, hypothetical protein FLJ20113, and activator of hsp90 ATPase homologue 1 (AHA1) revealed levels comparable between DS and controls.
|
15176487 |
2004 |
Primary differentiated carcinoma of thyroid gland
|
0.010 |
Biomarker
|
disease |
BEFREE |
In addition, we confirmed three previously reported loci (FOXE1, NKX2-1 and DIRC3) and identified seven novel susceptibility loci (VAV3, PCNXL2, INSR, MRSB3, FHIT, SEPT11 and SLC24A6) associated with DTC.
|
28703219 |
2017 |
Acute lymphocytic leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Reverse transcriptase-polymerase chain reaction revealed expression of a chimeric MLL-SEPT11 transcript, thus identifying what is to our knowledge a hitherto undescribed translocation in ALL.
|
20633769 |
2010 |
Childhood Acute Lymphoblastic Leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Reverse transcriptase-polymerase chain reaction revealed expression of a chimeric MLL-SEPT11 transcript, thus identifying what is to our knowledge a hitherto undescribed translocation in ALL.
|
20633769 |
2010 |
Adult Acute Lymphocytic Leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Reverse transcriptase-polymerase chain reaction revealed expression of a chimeric MLL-SEPT11 transcript, thus identifying what is to our knowledge a hitherto undescribed translocation in ALL.
|
20633769 |
2010 |