PRKD1, protein kinase D1, 5587

N. diseases: 171; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.350 Biomarker group CTD_human Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. 25240283 2014
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.350 GeneticVariation group BEFREE The PRKD1 E710D hotspot mutation is highly specific in separating polymorphous adenocarcinoma of the palate from adenoid cystic carcinoma and pleomorphic adenoma on FNA. 29266837 2018
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.350 GeneticVariation group BEFREE Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. 25240283 2014
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.350 GeneticVariation group BEFREE Polymorphous (low-grade) adenocarcinomas are characterized by hot spot point E710D mutations in the PRKD1 gene, whereas cribriform adenocarcinoma of (minor) salivary glands origin are characterized by translocations involving the PRKD1-3 genes. 29076877 2018
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.350 GeneticVariation group BEFREE Salivary gland polymorphous low-grade adenocarcinomas commonly harbor activating PRKD1 mutations. 25367945 2014
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.350 GeneticVariation group BEFREE Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland. 26426580 2016