MAPK1, mitogen-activated protein kinase 1, 5594

N. diseases: 1059; N. variants: 13
Disease: Schizophrenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.340 GeneticVariation disease BEFREE Concerning SCZ risk, we partially confirmed the associations among COMT and MAPK1 genetic variants and SCZ. 29164477 2018
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.340 Biomarker disease BEFREE We hypothesized pallidin and p38 play a role in neural system development and the pathogenesis of schizophrenia, and designed several experiments to test this possibility. 28035416 2017
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.340 AlteredExpression disease BEFREE Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics. 28214564 2017
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.340 Biomarker disease BEFREE ULK4 modulates multiple signalling pathways that include ERK, p38, PKC and JNK, which are involved in stress responses and implicated in schizophrenia. 24284070 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.340 Biomarker disease PSYGENET There were significant increase in ERK2, c-fos and c-jun protein and mRNA levels in thalamus of patients with schizophrenia relative to controls. 15380860 2004