MAPK1, mitogen-activated protein kinase 1, 5594

N. diseases: 1059; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia
0.350 Biomarker disease BEFREE Recombinant CC16 inhibits NLRP3/caspase-1-induced pyroptosis through p38 MAPK and ERK signaling pathways in the brain of a neonatal rat model with sepsis. 31775794 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.350 Biomarker disease BEFREE Our results suggest that MALAT1 aggravates cardiac inflammation and dysfunction in sepsis, which is achieved via interaction with miR-125b and p38 MAPK/NFκB. 29227823 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.350 Biomarker disease BEFREE These protective effects were mediated through MPLA stimulation of a Toll/IL-1 receptor domain-containing adaptor-inducing IFN-β-(TRIF)-dependent phosphatidylinositol 3-kinase-Akt pathway that prevents sepsis- and LPS-induced ERK activation. 29741098 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.350 Biomarker disease BEFREE Further studies are needed to illuminate the detailed mechanisms of JNK and p38 MAPK signaling in sepsis‑induced ARDS. 29039541 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.350 AlteredExpression disease BEFREE Up-regulation of miR-135a could aggravate sepsis-induced inflammation and myocardial dysfunction via activation of p38 MAPK/NF-κB pathway. 28147298 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.350 Biomarker disease CTD_human Role of chemically modified tetracycline on TNF-alpha and mitogen-activated protein kinases in sepsis. 15489642 2004