MAPK8, mitogen-activated protein kinase 8, 5599

N. diseases: 520; N. variants: 4
Disease: Dermatitis, Atopic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.320 AlteredExpression disease BEFREE This research has shown upregulated Fas, FasL, p-ERK, p-p38, and p-JNK expression along with increased cytokine secretion (IL-1β, IL-4, IL-8, IL-10, IL-12p70, IL-13, IL-17A, IL-31 and TNFα) by keratinocytes derived from the skin of patients with the AD when compared with healthy control. 30286163 2018
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.320 Biomarker disease BEFREE Activation of RhoA, Smad2, c-Src, PKC-βII/δ and JNK in atopic dermatitis. 29498756 2018
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.320 Biomarker disease CTD_human JNK1-/- mice showed less ear thickening and infiltration of eosinophils and mast cells in AD-like lesions than did WT mice when treated with MC903. 24046278 2013