Disease: HIV-1 infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 AlteredExpression disease BEFREE Using various reporter systems and <i>in vitro</i> kinase assays, we establish in this report that interactions between PACT, ADAR1 and HIV-1-encoded Tat protein diminish the activation of PKR in response to HIV-1 infection. 28167698 2017
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 AlteredExpression disease BEFREE However, PKR is not activated upon HIV-1 infection when the virus reaches high levels of replication, due to viral and cellular controls. 21294215 2011
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 Biomarker disease BEFREE Our results demonstrate that PKR can be effectively delivered to HSC by a lentiviral vector and can protect CD34-derived T cell progeny from HIV-1 infection. 15957958 2005
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 GeneticVariation disease BEFREE Specifically, expression of CD4 is upregulated by the PKR mutants, and this correlates with an induction of HIV-1 binding and proviral DNA synthesis upon HIV-1 infection. 8995707 1997