|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Responsiveness to dopamine agonists; deterioration of hyperprolactinemia may be diagnostic for prolactin-producing uterine leiomyomas, although further research is required.
|
28925774 |
2018 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Significant higher level of prolactin was found in FEP group than in CHR group (mean = 28.93 ± 27.16 vs 14.29 ± 7.86, P = 0.009), suggesting a condition of hyperprolactinemia (HPRL).
|
30068291 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
In this DMET microarray platform, we found three UGT1A1 variants with suggestive evidences of association with the risperidone-induced prolactin response both measured by hyperprolactinemia and by prolactin level.
|
29955115 |
2018 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Patients with PCOS and hyperprolactinaemia had LH-predominant secretion in keeping with increased GnRH pulsatility despite a raised prolactin level.
|
29660734 |
2018 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Half of patients with high PRL level had remission after treatment of hyperprolactinemia (p = .001).
|
29694255 |
2018 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Here, it is revealed that hyperprolactinemia promotes an increased expression of prolactin receptors in granulocytes.
|
29874677 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
L-dopa is a natural inhibitor of prolactin (PRL) hormone which is required to maintain lactation in women but it's over production (hyperprolactinemia) plays critical role in advancement of breast cancer.
|
29427634 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Many antipsychotics cause serum hyperprolactinemia as an adverse side effect; prolactin-Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT5) signaling both induces cell differentiation and suppresses apoptosis.
|
29778097 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
To identify a serum prolactin (PRL) cut-off value indicative of a PRL-producing adenoma in women with polycystic ovarian syndrome (PCOS) and hyperprolactinaemia and characterize such patients.
|
29845629 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our findings support a possible role of prolactin in emerging psychosis and it could be speculated that stress, which can induce hyperprolactinemia, has a stronger effect on women than on men in emerging psychosis.
|
28214176 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
From a total of 174 people with serum prolactin measurements at study recruitment, 43% (n=74) had HPL, whilst 27% (n=21/78) and 27% (n=26/95) had HPL at 3 and 12months respectively.
|
28755878 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Key aspects include asymptomatic hyperprolactinemia monitoring and fertility considerations with PRL normalisation.
|
28889207 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Some studies have reported that hyperprolactinemia is more common in RA and serum PRL levels are correlated with several disease parameters, although others could not confirm these findings.
|
28690611 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
A total of 95% of the 20 patients with hyperprolactinemia had progressive disease (PD), according to CT results, whereas only 2 patients (33%) out of 6 with stable PRL levels had PD (p = 0.004).
|
28407622 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
We aimed to determine if the observed hyperprolactinemia is due to a vascular-derived or known prolactin secretagogue from the injured ICA, analogous to pregnancy-associated hyperprolactinemia putatively due to placental factors.
|
28828544 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Antipsychotics are the most common pharmacological agents which cause hyperprolactinemia The aim of this review is to describe PRL physiology, PRL biological effects and pathway to the diagnosis, causes, consequences of HPRL focusing on the antipsychotic effects on the PRL.
|
28440197 |
2017 |
|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study was to estimate the association between hyperprolactinemia and all-cause and cardiovascular mortality among patients referred for assessment of prolactin.
|
28437810 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Serum prolactin revisited: parametric reference intervals and cross platform evaluation of polyethylene glycol precipitation-based methods for discrimination between hyperprolactinemia and macroprolactinemia.
|
28236625 |
2017 |
|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Prolactin gene polymorphism (-1149 G/T) is associated with hyperprolactinemia in patients with schizophrenia treated with antipsychotics.
|
27776952 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Hyperprolactinemia has been found in patients with systemic lupus erythematosus (SLE), and new evidence has confirmed a significant correlation between serum PRL levels and disease activity.
|
28130617 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adjunctive metformin appears to be effective and safe for reducing antipsychotic-induced hyperprolactinemia and prolactin-related symptoms in schizophrenia patients.
|
28372526 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
However, high PRL levels derived from prolactinoma and hyperprolactinemia induce physiological disorders such as infertility and early menopause.
|
28259983 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The symptoms of hyperprolactinemia are correlated to the levels of monomeric PRL excess, which may be explained as coincidental, by dissociation of macroprolactin, or by physiological, pharmacological and pathological causes.
|
29241908 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
High and middle dose of selfheal extract significantly reduced PRL level in hyperprolactinemia rat compared with model group (P< 0.01).
|
28946556 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Elevated prolactin levels (hyperprolactinemia) are a frequent adverse effect of antipsychotic medications, especially in young populations.
|
28660406 |
2017 |