RELN, reelin, 5649

N. diseases: 178; N. variants: 52
Disease: Major Depressive Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.500 Biomarker disease PSYGENET We have hypothesized that the extracellular matrix protein reelin is involved in the pathogenesis of major depression. 23608736 2013
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.500 Biomarker disease PSYGENET A number of neuropsychiatric disorders including autism, schizophrenia, bipolar disorder, major depression, Alzheimer's disease and lissencephaly share a common feature of abnormal Reelin expression in the brain. 22981949 2013
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.500 Biomarker disease CTD_human We present new immunocytochemical evidence showing reductions in Reelin expression in hippocampus of subjects with schizophrenia, bipolar disorder and major depression and confirm recent reports documenting a similar deficit involving Reelin expression in brains of subjects with schizophrenia and bipolar disorder. 11126396 2000