PSEN1, presenilin 1, 5663

N. diseases: 369; N. variants: 155
Disease: Cognitive deterioration ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0854193
Disease: Cognitive deterioration
Cognitive deterioration 		0.010 GeneticVariation disease BEFREE PSEN1 mutation carriers undergo the course of cognitive deterioration, which is typical for sporadic Alzheimer's disease but disease onset is earlier and disease progression is faster. 17012294 2006