B2M, beta-2-microglobulin, 567

N. diseases: 352; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1855796
Disease: Hypoproteinemia, Hypercatabolic
Hypoproteinemia, Hypercatabolic
0.710 Biomarker disease GENOMICS_ENGLAND β2-Microglobulin deficiency causes a complex immunodeficiency of the innate and adaptive immune system. 25702838 2015
CUI: C1855796
Disease: Hypoproteinemia, Hypercatabolic
Hypoproteinemia, Hypercatabolic
0.710 GeneticVariation disease BEFREE We concluded that a beta(2)m gene mutation underlies the hypercatabolism and reduced serum levels of albumin and IgG in the two siblings with familial hypercatabolic hypoproteinemia. 16549777 2006
CUI: C1855796
Disease: Hypoproteinemia, Hypercatabolic
Hypoproteinemia, Hypercatabolic
0.710 GeneticVariation disease UNIPROT Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2-microglobulin gene. 16549777 2006
CUI: C1855796
Disease: Hypoproteinemia, Hypercatabolic
Hypoproteinemia, Hypercatabolic
0.710 CausalMutation disease CLINVAR
CUI: C1855796
Disease: Hypoproteinemia, Hypercatabolic
Hypoproteinemia, Hypercatabolic
0.710 Biomarker disease CTD_human
CUI: C0268389
Disease: Amyloidosis, familial visceral
Amyloidosis, familial visceral
0.700 Biomarker disease GENOMICS_ENGLAND Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin. 22693999 2012
CUI: C0268389
Disease: Amyloidosis, familial visceral
Amyloidosis, familial visceral
0.700 Biomarker disease GENOMICS_ENGLAND Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin. 22693999 2012
CUI: C0268389
Disease: Amyloidosis, familial visceral
Amyloidosis, familial visceral
0.700 GeneticVariation disease UNIPROT Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin. 22693999 2012
CUI: C0268389
Disease: Amyloidosis, familial visceral
Amyloidosis, familial visceral
0.700 CausalMutation disease CLINVAR
CUI: C0268389
Disease: Amyloidosis, familial visceral
Amyloidosis, familial visceral
0.700 Biomarker disease CTD_human
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.500 Biomarker disease CTD_human A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers. 28885000 2017
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.500 Biomarker disease CTD_human Decrease in urinary creatinine in acute kidney injury influences diagnostic value of urinary biomarker-to-creatinine ratio in rats. 22005293 2011
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.500 Biomarker disease RGD Discrepancy between serum levels of low molecular weight proteins in acute kidney injury model rats with bilateral ureteral obstruction and bilateral nephrectomy. 19536607 2009
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.500 Biomarker disease CTD_human The effects of diltiazem on methotrexate-induced nephrotoxicity. 2689182 1989
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 AlteredExpression group BEFREE Lower serum level of β2-microglobulin and lower level of free light chain at diagnosis, achieving at least VGPR, and shorter kidney disease history are related to a high probability of dialysis independence in NDMM patients with serious renal failure requiring dialysis. 31663630 2020
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group BEFREE Patients who had AIP with IgG4-RKD were more likely to have extrapancreatic lesions other than those in the kidney, and their serum creatinine and urinary β2-microglobulin concentrations were significantly higher than in those without IgG4-RKD. 30826634 2019
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group BEFREE The detection of B2M and CC16 with the C18 plate-MALDI-TOF MS approach could be an attractive and practical assay for rapid diagnosis of nephropathy in nondiabetic/diabetic patients and as a predictor of ERFD among T2D patients who had not manifested significant kidney disease at baseline. 30024955 2018
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group BEFREE This study will provide important data about the local epidemiology of kidney disease in a high-risk rural setting and the utility of emerging renal filtration markers (Beta 2 Microglobulin and Cystatin C), while generating data and methods for the analyses of microRNA biomarkers. 29486722 2018
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 AlteredExpression group BEFREE We assessed if elevated levels of B2M would associate with either the diagnosis of AKI [under current Kidney Disease: Improving Global Outcomes (KDIGO) criteria] or recovery from AKI. 30524714 2018
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group BEFREE Rediscovering Beta-2 Microglobulin As a Biomarker across the Spectrum of Kidney Diseases. 28664159 2017
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group BEFREE Beta-2-microglobulin (B2M) expression in the urinary sediment correlates with clinical markers of kidney disease in patients with type 1 diabetes. 27173460 2016
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group CTD_human Identification of urinary miRNA biomarkers for detecting cisplatin-induced proximal tubular injury in rats. 24863737 2014
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group CTD_human Estimation of benchmark dose for pancreatic damage in cadmium-exposed smelters. 17303580 2007
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group BEFREE In fact, in this review, the editors have chosen to review the beta 2-microglobulin amyloid of long-term hemodialysis in the section on renal disease. 1543671 1992
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.480 Biomarker group CTD_human Assessment of urinary rat beta 2-microglobulin by enzyme immunoassay. 2202081 1990