PTGER1, prostaglandin E receptor 1, 5731

N. diseases: 44; N. variants: 1
Disease: Hyperalgesia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.310 GeneticVariation phenotype BEFREE The effects of the COX-2 inhibitor, parecoxib (intraperitoneal 10 mg kg<sup>-1</sup>), or the EP-1R antagonist, SC51089 (intraperitoneal 100 μg kg<sup>-1</sup>), on hyperalgesia and spinal PGE2 were examined. 29576123 2018
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.310 Biomarker phenotype CTD_human These results demonstrate that spinal EP1 receptors are involved in the PGE2-induced allodynia and that spinal EP3 receptors are involved in the hyperalgesia induced by low doses of PGE2. 11375261 2001