PTGS1, prostaglandin-endoperoxide synthase 1, 5742

N. diseases: 318; N. variants: 36
Disease: Intestinal Polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021846
Disease: Intestinal Polyps
Intestinal Polyps 		0.300 Biomarker phenotype CTD_human Recently, genetic disruption of COX-1, the other isoform, was shown to decrease the number of intestinal polyps and prostaglandin E(2) levels in intestinal mucosa, like the case with COX-2 gene disruption, in Min mice. 12189188 2002
CUI: C0021846
Disease: Intestinal Polyps
Intestinal Polyps 		0.300 Biomarker phenotype CTD_human Chemoprevention of familial adenomatous polyposis development in the APC(min) mouse model by 1,4-phenylene bis(methylene)selenocyanate. 10753194 2000