MIR506, microRNA 506, 574511

N. diseases: 76; N. variants: 1
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 AlteredExpression disease BEFREE Spearman correlation analysis revealed that expression of NR4A1 mRNA was negatively correlated with miR-506 levels in colorectal cancer tissue. 31293661 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 Biomarker disease BEFREE We found a significant elevated expression of both examined microRNAs in early CRC patients when compared to those in healthy individuals (p = 0.0054 for miR-506 and p = 0.0025 for miR-4316). 28405738 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 AlteredExpression disease BEFREE In the present study, in ISH and qRT-PCR results demonstrated that miR-506 is weakly expressed in chemoresistant CRC tissues. 28217977 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 Biomarker disease BEFREE In conclusion, our data showed that miR-124 and miR-506 inhibit progression and increase sensitivity to chemotherapy by targeting DNMT3B and DNMT1 in CRC. 26497367 2015