MIR506, microRNA 506, 574511

N. diseases: 76; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 AlteredExpression phenotype BEFREE We observed that miR-506 expression was upregulated in both CSCC tissues and cell lines, and that decreased miR-506 expression led to repressed tumorigenesis in CSCC cells. 30646812 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 Biomarker phenotype BEFREE Here, the impact of miR-506 on RB cell survival in vitro and tumorigenesis in vivo was examined. 31571997 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 Biomarker phenotype BEFREE The present study was aimed to investigate the character of miR-506 and some related factors in human osteosarcoma (OS) carcinogenesis. 28926924 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 Biomarker phenotype BEFREE Our results suggest that miR-506 either plays a role as an oncogene in the tumorigenesis and a tumor suppressor in the progression or serves as a house-keeping, tumor-suppressing miRNA, whose expression can be activated by oncogenic signals in early development to hinder the progression of PDAC. 27371108 2016
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 Biomarker phenotype BEFREE Increasing evidence indicates that microRNA (miR)-506 plays a vital role in tumorigenesis; however, the role of miR-506 in gastric cancer (GC) is unclear and needs further investigation. 25846731 2015
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 Biomarker phenotype BEFREE Furthermore, we demonstrated that miR-506 mimics inhibited tumorigenesis in vivo, implicating that miR-506 might be a potential therapeutic molecule for selective killing of lung cancer cells. 24469051 2015
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 Biomarker phenotype BEFREE We further showed that expression of miR-506-3p, but not miR-124-3p, is dramatically upregulated in differentiated neuroblastoma cells, suggesting the important role of endogenous miR-506-3p in differentiation and tumorigenesis. 24811707 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 Biomarker phenotype BEFREE MiR-506 is a miRNA involved in carcinogenesis of several kinds of cancer. 25087998 2014