PTK2, protein tyrosine kinase 2, 5747

N. diseases: 205; N. variants: 21
Disease: Hepatoblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.220 AlteredExpression disease BEFREE Finally, increased expression of PTK2 and reduced expression of FADD both led to the inhibition of cell apoptosis, thus promoting the tumorigenesis of hepatoblastoma. 30367502 2019
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.220 Biomarker disease BEFREE In the present study, a small‑molecule FAK inhibitor, 1,2,4,5-benzenetetramine tetrahydrochloride (Y15), was used to study the effects of FAK inhibition on the adhesion and migration behaviors of vascular endothelial cells (VECs) and human hepatoblastoma cells. 29484384 2018
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.220 Biomarker disease RGD Marked suppression of tumor growth by FTY720 in a rat liver tumor model: the significance of down-regulation of cell survival Akt pathway. 17203219 2007