ARRDC3, arrestin domain containing 3, 57561

N. diseases: 24; N. variants: 1
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE The most significant gene, ARRDC3, is a member of the arrestin family of proteins, and evidence in animal models and human data suggests that this gene is a regulator of obesity and energy expenditure. 31187853 2019
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE The arrestin domain containing protein Arrdc3 is a regulator of obesity in mice and also appears linked to obesity in humans. 28291835 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE These results demonstrate that ARRDC3 is a gender-sensitive regulator of obesity and energy expenditure and reveal a surprising diversity for arrestin family protein functions. 21982743 2011