ANKRD36B, ankyrin repeat domain 36B, 57730

N. diseases: 82; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma
0.100 Biomarker disease BEFREE Recombinant DNA technology for melanoma immunotherapy: anti-Id DNA vaccines targeting high molecular weight melanoma-associated antigen. 25027754 2014
CUI: C0025202
Disease: melanoma
melanoma
0.100 AlteredExpression disease BEFREE Human melanoma proteoglycan (HMP), a melanoma-associated antigen, is expressed in both human melanomas and gliomas. 19152070 2009
CUI: C0025202
Disease: melanoma
melanoma
0.100 Biomarker disease BEFREE Generated particles specifically transduced melanoma cell lines expressing the HLA-A1/MAGE-A1 target complex with at least 10-fold higher efficiency than control viruses. 18323790 2008
CUI: C0025202
Disease: melanoma
melanoma
0.100 Biomarker disease BEFREE The immunogenicity of malignant melanomas has been recognized by the observed recruitment of tumor-specific cytotoxic T-cells (CTL), leading to the identification of several melanoma associated antigen (MAA). 18831916 2008
CUI: C0025202
Disease: melanoma
melanoma
0.100 AlteredExpression disease BEFREE The lack of melanoma-associated antigen (MAA) expression has been associated with the reduced overall survival in melanoma patients. 15305155 2004
CUI: C0025202
Disease: melanoma
melanoma
0.100 Biomarker disease BEFREE Hence, the HMWMAA-targeted adenoviral vector lacking native tropism exhibits both enhanced specificity and augmented infectivity of gene transfer to melanoma cells, suggesting that it is feasible to use this vector to improve gene therapy for malignant melanoma. 14618628 2004
CUI: C0025202
Disease: melanoma
melanoma
0.100 Biomarker disease BEFREE Comprehensive analysis of the frequency of recognition of melanoma-associated antigen (MAA) by CD8 melanoma infiltrating lymphocytes (TIL): implications for immunotherapy. 11449353 2001
CUI: C0025202
Disease: melanoma
melanoma
0.100 GeneticVariation disease BEFREE Patients with melanoma with the HLA-A-24 phenotype were recruited for vaccination with the peptide AFLPWHRLF from the melanoma-associated antigen tyrosinase. 10746555 2000
CUI: C0025202
Disease: melanoma
melanoma
0.100 AlteredExpression disease BEFREE The notion that Pmel17/gp100 represents the biologically relevant target in this system was supported by the observations (i) that recipients of Pmel17/gp100 DNA mount an antigen-specific cytotoxic T lymphocyte response and (ii) that M3 tumors growing in mice immunized with autologous Pmel17/gp100 had lost expression of this melanoma-associated antigen whereas M3 melanomas appearing in control-vector-treated animals were still Pmel17/gp100-positive. 11121145 2000
CUI: C0025202
Disease: melanoma
melanoma
0.100 AlteredExpression disease BEFREE Cloning and in vitro expression of a melanoma-associated antigen immunogenic in patients with melanoma. 1861072 1991
CUI: C0025202
Disease: melanoma
melanoma
0.100 AlteredExpression disease BEFREE Cytotoxic activity toward mouse melanoma following immunization of mice with transfected cells expressing a human melanoma-associated antigen. 1674672 1991
CUI: C0025202
Disease: melanoma
melanoma
0.100 GeneticVariation disease BEFREE Thin melanomas showed a significant difference for the melanoma-associated antigen G7-E2 (higher expression in women) and the histocompatibility antigen HLA-DR (higher expression in men). 2066358 1991