Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation.
|
11278247 |
2001 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis.
|
11779501 |
2001 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export.
|
11925436 |
2002 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability.
|
12832489 |
2003 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
BEFREE |
Mutational analysis of BARD1 in familial breast cancer patients in Japan.
|
14550946 |
2003 |
Breast Cancer, Familial
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
These results suggest that the contribution of the BARD1 germline variants to breast cancer predisposition is very limited, and that neither Cys557Ser nor Val507Met have an effect on familial breast cancer susceptibility.
|
16333312 |
2006 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly.
|
17081976 |
2006 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.
|
18443292 |
2008 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
BEFREE |
We have found no evidence to support involvement of BARD1 in familial breast cancer risk in the Australian population.
|
17972171 |
2008 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
BARD1 homozygous deletion, a possible alternative to BRCA1 mutation in basal breast cancer.
|
20842729 |
2010 |
Breast Cancer, Familial
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
The BARD1 Cys557Ser variant and risk of familial breast cancer in a South-American population.
|
22544576 |
2012 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks.
|
26350354 |
2015 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
Inherited Mutations in Women With Ovarian Carcinoma.
|
26720728 |
2016 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk.
|
28649662 |
2017 |
Breast Cancer, Familial
|
0.350 |
Biomarker
|
disease |
CLINGEN |
Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer.
|
28418444 |
2017 |
Breast Cancer, Familial
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer.
|
31036035 |
2019 |