BARD1, BRCA1 associated RING domain 1, 580

N. diseases: 75; N. variants: 176
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 GeneticVariation group LHGDN BARD1 and breast cancer in Poland. 17333333 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 GeneticVariation group LHGDN Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies. 16825437 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 GeneticVariation group BEFREE To investigate whether alterations in BARD1 are involved in human breast and ovarian cancer, we used single strand conformation polymorphism analysis and sequencing on 35 breast tumours and cancer cell lines and on 21 ovarian tumours. 16061562 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 Biomarker group LHGDN Mutation screening of the BARD1 gene: evidence for involvement of the Cys557Ser allele in hereditary susceptibility to breast cancer. 15342711 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 AlteredExpression group LHGDN We examined the mRNA levels of TIEG, Smad7, Smad2, and Bard1 using real-time RT/PCR in 14 normal breast, five non-invasive, 57 invasive (including 29 with outcome data), and five metastatic breast tumor tissues. 15218362 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 Biomarker group CTD_human
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.450 CausalMutation group CLINVAR