PVALB, parvalbumin, 5816

N. diseases: 148; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.350 Biomarker disease BEFREE Our results indicate convergence of transcriptome studies of schizophrenia and bipolar disorder on changes in cortical astrocytes and fast-spiking parvalbumin interneurons, providing a unified interpretation of numerous studies. 30177255 2018
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.350 AlteredExpression disease BEFREE We used a combination of human postmortem and rodent studies to test the hypothesis that neurons expressing parvalbumin (PV neurons), a main TRN neuronal population, and associated Wisteria floribunda agglutinin-labeled perineuronal nets (WFA/PNNs) are altered in SZ and BD, and that these changes may occur early in the course of the disease as a consequence of oxidative stress. 29180672 2018
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.350 GeneticVariation disease BEFREE Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin. 23038240 2012
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.350 AlteredExpression disease BEFREE Reduced expression of parvalbumin, a marker of mature FS cells, has been reported in individuals with schizophrenia and bipolar disorder and in mouse models of schizophrenia and autism. 22936973 2012
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.350 Biomarker disease BEFREE We observed no differences in the relative density and laminar distribution of the PV-expressing neurons between subjects with bipolar disorder and matched normal control subjects. 20148871 2010
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.350 Biomarker disease CTD_human ANOVA with correction for multiple comparisons indicated that parvalbumin-containing cells in CA2 were reduced in schizophrenia and bipolar disorder. 14708030 2004