Malignant tumor of colon
|
0.010 |
Biomarker
|
disease |
BEFREE |
ABCD3, CPT2, AGL and JAM2 are potential biomarkers for the diagnosis of colon cancer.
|
29928385 |
2018 |
Colon Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
ABCD3, CPT2, AGL and JAM2 are potential biomarkers for the diagnosis of colon cancer.
|
29928385 |
2018 |
Primary familial brain calcification
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification.
|
31851307 |
2020 |
Necrotic enteritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Down-regulated expression levels of tight junction (TJ) proteins: junctional adhesion molecule 2 (JAM2), occluding, and intestinal mucin 2 (MUC2) by NE challenge, was up-regulated by the addition of AH (1 or 3%) supplementation.
|
29538713 |
2018 |
Encephalomyelitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Following immunization with MOG<sub>aa35-55</sub> peptide, JAM-B<sup>-/-</sup> mice developed ameliorated EAE compared to their wild-type littermates.
|
29920328 |
2018 |
Rheumatoid Arthritis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
HLA-C rs12212594 T/C, JAM2 rs2829866 A/T and REL rs702873 G/A polymorphisms were not associated with the risk of RA.
|
24566686 |
2014 |
Fibrosis, Liver
|
0.010 |
Biomarker
|
disease |
BEFREE |
Junctional adhesion molecules JAM-B and JAM-C promote autoimmune-mediated liver fibrosis in mice.
|
29753567 |
2018 |
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
MicroRNA-374 targets JAM-2 regulates the growth and metastasis of human pancreatic cancer cells.
|
31737197 |
2019 |
Psoriasis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Several genetic factors involved in the susceptibility to psoriasis and psoriatic arthritis (PsA) have been identified with genome-wide association studies, including human leukocyte antigen (HLA)-C, junction adhesion molecule 2 (JAM2) and REL.
|
24566686 |
2014 |
Arthritis, Psoriatic
|
0.010 |
Biomarker
|
disease |
BEFREE |
Several genetic factors involved in the susceptibility to psoriasis and psoriatic arthritis (PsA) have been identified with genome-wide association studies, including human leukocyte antigen (HLA)-C, junction adhesion molecule 2 (JAM2) and REL.
|
24566686 |
2014 |
Tumor Cell Invasion
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The key findings of the study demonstrated that miR-374b significantly inhibits cell proliferation, migration, and invasion through the blockade of the p38/ERK signaling pathway activation, as well as negatively binding to JAM-2, highlighting its potential as a therapeutic target for CC.
|
29575013 |
2018 |
Malignant tumor of cervix
|
0.010 |
Biomarker
|
disease |
BEFREE |
The key findings of the study demonstrated that miR-374b significantly inhibits cell proliferation, migration, and invasion through the blockade of the p38/ERK signaling pathway activation, as well as negatively binding to JAM-2, highlighting its potential as a therapeutic target for CC.
|
29575013 |
2018 |
Cervix carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The key findings of the study demonstrated that miR-374b significantly inhibits cell proliferation, migration, and invasion through the blockade of the p38/ERK signaling pathway activation, as well as negatively binding to JAM-2, highlighting its potential as a therapeutic target for CC.
|
29575013 |
2018 |
cervical cancer
|
0.010 |
Biomarker
|
disease |
BEFREE |
The key findings of the study demonstrated that miR-374b significantly inhibits cell proliferation, migration, and invasion through the blockade of the p38/ERK signaling pathway activation, as well as negatively binding to JAM-2, highlighting its potential as a therapeutic target for CC.
|
29575013 |
2018 |
Non-Small Cell Lung Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The present results indicate that miRNA-374b inhibits tumor growth and promotes apoptosis in NSCLC through the p38/ERK signaling pathway by targeting JAM-2.
|
30416798 |
2018 |
Hepatitis
|
0.010 |
Biomarker
|
group |
BEFREE |
Therefore, localization and function of JAM-B and JAM-C were investigated in three mouse models of autoimmune-driven liver inflammation.
|
29753567 |
2018 |
Alzheimer's Disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We identified several novel markers associated with AD, namely HOMER2 (rs1256429; intronic, p = 8.7 × 10⁻¹⁰), EOMES (rs2724509; flanking), JAM2 (rs2829841; intronic), and WEE1 (rs10770042; coding).
|
25649652 |
2015 |