RAC1, Rac family small GTPase 1, 5879

N. diseases: 415; N. variants: 20
Disease: Autistic Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.120 Biomarker disease BEFREE Moreover, considering the present data from our systems biology approach together with the results from the differential gene expression analysis of cerebellar samples from autistic patients, we believe that RAC1, in particular, and the RHO family of GTPases, in general, could play a critical role in the neuropathological events associated with autism. 23456597 2013
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.120 Biomarker disease BEFREE Dedicator of cytokinesis 4 (Dock4), an atypical guanine nucleotide exchange factor for Rac1, is found to be associated with neuropsychiatric diseases, including autism and schizophrenia. 23720743 2013
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.120 GeneticVariation disease GWASDB Individual common variants exert weak effects on the risk for autism spectrum disorders. 22843504 2012