RAC1, Rac family small GTPase 1, 5879

N. diseases: 415; N. variants: 20
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure
0.500 Biomarker disease CTD_human The majority of these mice displayed severe hypertrophy (heart-to-body weight ratios >2-fold greater in the Rac1 mice) and died from overt heart failure between days 14 and 17. 16155095 2005
CUI: C0018801
Disease: Heart failure
Heart failure
0.500 Biomarker disease RGD Alterations in G protein and MAP kinase signaling pathways during cardiac remodeling in hypertension and heart failure. 12642504 2003