|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Analysis of TCGA data revealed elevated RAD51 expression in breast tumors compared to normal breast tissues, especially in TNBC subtype.
|
31492187 |
2019 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
RAD51 foci formation and PALB2 LOH status were evaluated in primary breast tumor samples from the carriers.
|
30552643 |
2019 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
BEFREE |
F86L is a breast tumor-derived somatic variant that affects the interface between adjacent RAD51 protomers in the presynaptic filament.
|
29100040 |
2017 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Here we describe a set of mutations associated with human breast tumors that occur in a common structural motif of RAD51.
|
25539919 |
2015 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
LHGDN |
Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility.
|
18974064 |
2009 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
XRCC1 Arg399Gln and RAD51 5'UTR G135C polymorphisms and their outcome in tumor aggressiveness and survival of Portuguese breast cancer patients.
|
17616806 |
2008 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Dinucleotide repeat polymorphisms of RAD51, BRCA1, BRCA2 gene regions in breast cancer.
|
18429825 |
2008 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Loss of heterozygosity in the RAD51 and BRCA2 regions in breast cancer.
|
18632222 |
2008 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.
|
17999359 |
2007 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Genetic instability in the RAD51 and BRCA1 regions in breast cancer.
|
17180310 |
2007 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Altered DNA binding by the human Rad51-R150Q mutant found in breast cancer patients.
|
17666788 |
2007 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Notably, retrospective analyses of microarray expression data reveal elevated expression of RAD51 and two of its late-acting cofactors, RAD54 and RAD51AP1, in BRCA1-deficient versus sporadic breast tumors.
|
17942895 |
2007 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
RAD51 135G>C polymorphism and risk of familial breast cancer in a South American population.
|
17889711 |
2007 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The RAD51 gene region has been shown to exhibit loss of heterozygosity in breast tumours, and deregulated RAD51 expression in breast cancer patients has also been reported.
|
16762046 |
2006 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Analysis of RAD51 polymorphism and BRCA1 mutations in Polish women with breast cancer.
|
16837909 |
2006 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Polymorphisms of the BRCA2 and RAD51 genes in breast cancer.
|
16261408 |
2005 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association of breast tumor susceptibility gene products BRCA1 and BRCA2 with the RAD51 recombination protein suggested that cancer could arise through defects in recombination.
|
10362364 |
1999 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
CTD_human |
|
|
|