FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
|
20400964 |
2010 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer.
|
26740214 |
2016 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
|
27433846 |
2016 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
UNIPROT |
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
|
24141787 |
2014 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
RAD51C is a susceptibility gene for ovarian cancer.
|
21616938 |
2011 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Germline mutations in DNA repair genes may predict neoadjuvant therapy response in triple negative breast patients.
|
27328445 |
2016 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).
|
24315737 |
2014 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
|
20400963 |
2010 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
|
22167183 |
2012 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
|
26822949 |
2016 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment.
|
26270727 |
2015 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
|
20400963 |
2010 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population.
|
26261251 |
2015 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Germline RAD51C mutations confer susceptibility to ovarian cancer.
|
22538716 |
2012 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel.
|
26687385 |
2016 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Germline mutation in the RAD51B gene confers predisposition to breast cancer.
|
24139550 |
2013 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
|
26824983 |
2016 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.
|
26057125 |
2015 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
Biomarker
|
disease |
CLINGEN |
Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
|
22167183 |
2012 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2.
|
27616075 |
2017 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.
|
20400964 |
2010 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Identification of functional domains in the RAD51L2 (RAD51C) protein and its requirement for gene conversion.
|
12966089 |
2003 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
|
24141787 |
2014 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
CausalMutation
|
disease |
CLINVAR |
Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
|
25452441 |
2015 |
FANCONI ANEMIA, COMPLEMENTATION GROUP O
|
0.710 |
GeneticVariation
|
disease |
CLINVAR |
Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families.
|
22451500 |
2012 |