RAD51C, RAD51 paralog C, 5889

N. diseases: 162; N. variants: 96
Disease: Breast Cancer, Familial ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease BEFREE The analysis also showed a substantial difference in the profile of genes contributing to either BC or OC risk, including genes specifically associated with a high risk of OC but not BC (e.g., RAD51C, and RAD51D). 30733081 2019
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease BEFREE The aim of this study was to couple breast tumor sequencing with case-control data to clarify the contribution of RAD51C to hereditary breast cancer. 30949688 2019
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer. 28418444 2017
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Node retraction during patterning of the urinary collecting duct system. 25292187 2015
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families. 22451500 2012
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN RAD51C germline mutations in breast and ovarian cancer cases from high-risk families. 21980511 2011
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.320 Biomarker disease CLINGEN Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964 2010